355 research outputs found

    Spectrum Sensing Using CSMA Technique

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    Cognitive Radio is an emerging frontier to tackle the ever increasing demand of spectral needs. The most important function of CR is to search for spectrum holes or white spaces in the spectrum. Many techniques has been introduced and researched to increase the efficiency and accuracy of Spectrum Sensing. With the introduction of more complex methods cost of the whole process also increases. The following paper suggests a new idea of involving CSMA technique for spectrum sensing. This paper will give an insight on working of CR and CSMA technique. Later it will put forward the criterion for spectrum sensing and how CSMA can be used for investigate the presence of primary user in the spectrum vicinity

    The black bone disease: a case report of ochronotic hip arthropathy

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    Ochronotic arthropathy is a rare complication in patients with alkaptonuria (AKU) that arises as a result of accumulation of ochronotic pigment in the joints. This case report presented a 70-year-old female patient with chronic pain in B/L knee and right hip with decreased e range of motion. The physical and radiographic findings were agreeable with end-stage hip osteoarthritis and knee osteoarthritis. The diagnosis was done by finding of a dark capsule and femoral head during the total hip replacement. The surgical treatments significantly minimized and enhanced the range of motion (ROM). AKU normally emerges after age 40 and is normally asymptomatic till the involvement of the spine, hip, knee and shoulder joints. Therefore, orthopedic surgeons must be observant of clinical manifestations of this rare condition, before and during the surgery. Arthroplasty is an appropriate therapeutic recourse for patients suffering from ochronotic arthropathy

    Lack of Oncological Benefit from Bursectomy in Radical Gastrectomy: A Systematic Review

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    Background: Resection of the omental bursa has been suggested to reduce peritoneal recurrence and facilitate a complete oncological resection during a gastrectomy. The addition of this procedure increases technical complexity and prolongs the procedure. Published data regarding the oncological benefit of this procedure are conflicting. We hypothesized that a bursectomy during a radical gastrectomy does not improve overall survival. Methods: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guideline, a comprehensive literature search of 3 electronic databases (PubMed, Scopus, and Embase) was conducted to identify the clinical studies that compared bursectomy with no-bursectomy in radical gastrectomy for gastric adenocarcinoma. Qualitative and quantitative data synthesis was performed using RevMan software. A random-/fixed-effect modeling was used depending upon the heterogeneity. Bias and quality assessment tools were applied. The study was registered with the International Prospective Register of Systematic Reviews (PROSPERO) (CRD42019116556). Results: Of 8 studies assessing the role of bursectomy in gastric adenocarcinoma, 6 (75%) were included – of which 2 (33%) are randomized controlled trials. Of 2,904 patients, 1,273 (%) underwent a bursectomy. There was no statistically significant difference in either overall survival (hazard ratio [HR] = 0.89, 95% CI 0.75–1.06, I2 = 14%) or disease recurrence (HR = 1.01, 95% CI 0.84–1.20, I2 = 22%) in the bursectomy group compared to the no-bursectomy group. Conclusion: There is no additional oncological benefit of adding bursectomy to radical gastrectomy in all patients with gastric adenocarcinoma

    Quality assessment of value-added Indian recipe pedakiya prepared from composite flour and sesame seeds.

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    The present study was designed to enhance the nutritional value of the Indian recipe pedakiya/gujiya, a traditional sweet deep-fried dumpling, by utilizing the beneficial properties of composite flour (oat and peas flour) and sesame seeds. Furthermore, the study aimed to investigate the effects of partial substitution of refined wheat flour with oat and peas flour on nutritional, sensory, and microbiological parameters as affected by different cooking (deep-fat frying, baking, and air-frying) methods. The dough was developed by partially substituting a high percentage of refined wheat flour with oat flour, peas flour, and sesame seeds and based on the different treatments, these were coded as P0 (control), P1 (value-added pedakiya processed by deep-fat frying at 120 °C /5 minutes), P2 (air-fried at 120 °C  /30 minutes), and P3 (baked at 200 °C /25 minutes). Based on sensory evaluation, sample P1 was the most acceptable by the sensory panel. Chemical analyses revealed that the addition of composite flour and sesame seeds substantially increased the nutritional parameters of the product. The product's microbiological analyses revealed that, up to a 15-day storage period, the product was well within safe levels. Aluminum bags were determined to be a suitable packaging material for storing the value-added pedakiya based on the water activity (at 37 °C/91% RH) and overall acceptability scores. This study has provided an alternative approach for preparing traditional pedakiya by utilizing healthier options. The topic of the present study is very timely since consumers are constantly looking for better alternatives to traditional fried dishes

    SYNTHESIS AND EVALUATION OF SOME BENZOTHIAZOLE DERIVATIVES AS ANTIDIABETIC AGENTS

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    Objective: The objective of the present research investigation involves synthesis and biological evaluation of antidiabetic activity of benzothiazole derivatives.Methods: A novel series of benzothiazole derivatives 7(a-l) were synthesised and synthesised compounds were characterised for different physical and chemical properties like molecular formula, molecular weight, melting point, percentage yield, Rf value, IR, 1HNMR, 13CNMR and mass spectroscopy. The newly synthesised benzothiazole derivatives were subsequently assayed in vivo to investigate their hypoglycemic activity by the alloxan-induced diabetic model in rats. Results: All the synthesised derivatives showed significant biological efficacy. The compound 7d at 350 mg/kg exerted maximum glucose lowering effects whereas 7c showed minimum glucose lowering effects. All the compounds were effective, and experimental results were statistically significant at p<0.01 and p<0.05 level.Conclusion: From the results, it is clear that compound 7d demonstrated potent anti-diabetic activity and would be of better use in drug development to combat the metabolic disorder in future

    TECHNIQUES USED FOR BIOCHEMICAL INVESTIGATION IN RELATION TO FORENSIC ANALYSIS

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    The aim of this review was to apply the knowledge & technology of science for the definition & enforcement of such laws. The forensic analysis is investigation the crime and examines material evidence. In forensic analysis various biochemical investigation techniques are used to examine the crimes like Hair analysis, Polygraphic test, serology test and finger print analysis. Several instruments are used in forensic analysis like IR, Chromatography, UV and Mass spectrophotometer. The characterization results showed that Forensic pharmacists engage in work relating to litigation, the regulatory process, or the criminal justice system

    DESIGN, DEVELOPMENT AND EVALUATION OF LIPID BASED TOPICAL FORMULATIONS OF SILVER SULFADIAZINE FOR TREATMENT OF BURNS AND WOUNDS

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    Abstract: The aim of this research was to develop a novel lipid based film forming gel based on polymer and to investigate its potential as slow-release wound healing vehicle. The lipid based is composed of water soluble gel with model drug (Silver Sulfadiazine) and an egg oil, which acted as a remove scars. The morphology, rheology, mechanical properties, in-vitro drug release profiles were investigated. A smooth film layers was produced. The characterization results showed that film has superior mechanical and rheological properties than the ointment and cream. The lipid based gel treating low suppurating wounds and suitable for slow release application on wound surfaces. The lipid based gel also provided a significant higher healing rate in-vivo, with well-formed epidermis with faster granulation tissue formation when compared to the controls. In conclusions, a novel polymer-based lipid film gel was developed and results suggested that they can be exploited as slow-release wound dressings. Key Words: Wound healings, slow release, silver sulfadiazine and film ge

    Integrative Therapy based on Yoga, Ayurveda and Modern Western Medicine for treatment of high-risk cases of COVID-19: A telemedicine-based case series

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    We report a telemedicine-based case-series of 30 mild/moderate (classification based on guidelines by Ministry of Health and Family Welfare, Government of India) COVID-19 patients, treated using Integrative Therapy based on Ayurveda, Yoga and Modern Western Medicine, i.e., MWM (allopathy). Cases were high-risk owing to comorbidities like Diabetes Mellitus, Hypertension, Coronary Artery Disease, Ulcerative colitis, Chronic Kidney Disease and/or age above 60. The cases have been categorized into YAS (Yoga-Ayurveda based treatment, with possibly allopathic Supplements: 4 patients), YASP (Yoga-Ayurveda based treatment, with possibly allopathic Supplements and Paracetamol: 6 patients), YAM (Yoga-Ayurveda based treatment, and MWM as adjunct: 6 patients), MYA (first tried MWM, later switched to Yoga-Ayurveda: 14 patients). Based on each patient’s symptoms and co-morbidities, a personalized treatment plan including Ayurvedic medicines, Yoga protocol, dietary recommendations and lifestyle modifications was prescribed by a registered Ayurveda doctor and a Yoga consultant. More than half of symptomatic patients started improving within 5 days (90% within 9 days); more than 60% reported at least 90% recovery within 10 days. Six patients with oxygen saturation (SpO2) below 95%, benefited through Makarasana and Shithilasana; none progressed to composite endpoints (consisting of admission to Intensive Care Unit, invasive ventilation or death). Considering that approximately 19.3% of the patients with these comorbidities progress to composite end points, the p-value is 7.21 x 10−3. The Integrative Therapy, incorporating Yoga and Ayurveda with MWM, may offer an economical, scalable treatment option for COVID-19 by reducing burden on healthcare facilities and preventing risk-exposure of healthcare workers
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